MyoStrain® Provides Quantitative Heart Failure Risk Assessment to Help Clinicians Individualize and Monitor Treatment in Asymptomatic Patients With Non-Ischemic Cardiomyopathy

MORRISVILLE, N.C., April 20, 2021 – A new article published in the Journal of Cardiovascular Magnetic Resonance utilized MyoStrain (fast-SENC) to accurately risk-stratify asymptomatic cardiac patients across multiple disease states. The article demonstrated MyoStrain’s clinical utility as a critical risk stratification tool to help clinicians improve treatment decisions and optimize care.[1]

The study compared MyoStrain’s ability to quantify and differentiate patients based on their cardiac risk versus traditional ejection faction. Observers examined patients present with chronic non-ischemic heart failure caused by dilated cardiomyopathy, hypertrophic cardiomyopathy or cardiac amyloidosis.[1]

MyoStrain enabled clinicians to accurately describe the impact of the disease on patient heart function and plot each patient subject along MyoStrain’s progressive dysfunction curve, a risk stratification tool that allows clinicians to individually classify patients in terms of the ACC/AHA guidelines for heart failure stages. [1],[2]

Professor Henning Steen, MD, Head of Cardiac MRI at Marien Hospital in Hamburg, Germany, and lead author of the article, stated: “MyoStrain offers the visibility needed to help clinicians assess early asymptomatic dysfunction in our patients. It uses a unique and highly sensitive technique to acquire segmental strain, which provides us both the ability to detect and subsequently categorize these patients into risk groups based on the individual patterns and severity of their dysfunction.”

Professor Grigorios Korosoglou, MD, Chief of Cardiology & Vascular Medicine at GRN Hospital and the principal investigator of the study, added: “This study has shown that MyoStrain provides a critical cardiac risk assessment and management tool for patients at risk of heart failure. Through its progressive curve, MyoStrain helps clinicians to not only determine a patient’s risk of developing heart failure, but to individualize care as well by monitoring the effectiveness of treatment on the patient overtime. This may allow clinicians to focus on preventing the progression of heart dysfunction early on for improved clinical outcomes and quality of life for patients.”

Full access to the publication is available here.

[1] Steen, H., et al. J Cardiovasc Magn Reson 23, 45(2021). https://doi.org/10.1186/s12968-021-00711-w

[2] Korosoglou, G et al. J Am Coll Cardiol Cardiovasc Imaging. Jan 13, 2021.DOI: 10.1016/j.jcmg.2020.10.024