Publications

Research Highlights

Hyperventilation/Breath-Hold Maneuver to Detect Myocardial Ischemia by Strain-Encoded CMR: Diagnostic Accuracy of a Needle-Free Stress Protocol
This article demonstrates MyoStrain’s speed and sensitivity to successfully measure cardiac stress during a safe, simple hyperventilation breathing maneuver. Performed without any pharmacological or physical stress protocols, this new technique may provide clinicians with a faster and safer quantitative stress test to help improve the diagnosis and management of coronary artery disease.
JACC Cardiovascular Imaging
April 15, 2021
Strain‐encoded magnetic resonance: a method for the assessment of myocardial deformation
This clinical review article describes the history and evolution of the MyoStrain technology. The manuscript itself provides a detailed summary of existing literature about MyoStrain and its predecessor technologies HARP and SENC, totaling 400+ publications representing 70,000+ patient data points to date.
ESC Heart Failure Journal
April 25, 2019

All MyoStrain® Publications

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Left and right ventricular strain using fast strain-encoded cardiovascular magnetic resonance for the diagnostic classification of patients with chronic non-ischemic heart failure due to dilated, hypertrophic cardiomyopathy or cardiac amyloidosis
The study compared MyoStrain’s ability to quantify and differentiate asymptomatic patients based on their cardiac risk versus traditional ejection faction, reiterating the technology's potential as a critical cardiac risk stratification tool enabling clinicians to identify at-risk patients early for individualized preventative treatment.
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April 5, 2021
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Journal of Cardiovascular Magnetic Resonance
Hyperventilation/Breath-Hold Maneuver to Detect Myocardial Ischemia by Strain-Encoded CMR: Diagnostic Accuracy of a Needle-Free Stress Protocol
This article demonstrates MyoStrain’s speed and sensitivity to successfully measure cardiac stress during a safe, simple hyperventilation breathing maneuver. Performed without any pharmacological or physical stress protocols, this new technique may provide clinicians with a faster and safer quantitative stress test to help improve the diagnosis and management of coronary artery disease.
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April 15, 2021
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JACC Cardiovascular Imaging
Quantitative detection of changes in regional wall motion using real time strain-encoded cardiovascular magnetic resonance
In this article, MyoStrain provides a rapid and quantitative assessment of segmental myocardial strain to help reliably detect ischemia in patients suspected in coronary artery disease.
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September 1, 2019
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Journal of Magnetic Resonance Imaging
Strain-Encoded Cardiac Magnetic Resonance During High-Dose Dobutamine Stress Testing for the Estimation of Cardiac Outcomes
This paper demonstrates MyoStrain's clinical utility in the rapid assessment and quantification of ischemia to help guide clinical decision-making for chest pain patients entering the ER.
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September 6, 2011
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JACC Cardiovascular Imaging
Strain-Encoded CMR for the Detection of Inducible Ischemia During Intermediate Stress
This paper utilizes MyoStrain's non-invasive stress test technique to identify subtle changes in heart function indicative of ischemia in patients suspected of coronary artery disease.
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April 1, 2010
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JACC Cardiovascular Imaging
Interim study: analysis of myocardial deformation using fSENC-CMR on patients with chest pain
In this abstract, authors utilize MyoStrain's non-invasive hyperventilation stress test to help physicians detect ischemic coronary artery disease in chest pain patients entering the ER.
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August 31, 2019
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Abstract at ESC Congress 2019
CMR fast-SENC intramyocardial LV & RV segmental strain helps manage cardioprotective therapy in patients exhibiting cardiotoxicity during cancer treatment
This abstract demonstrates the clinical application of MyoStrain as a tool to help quantify, monitor, and manage cardio-protection for oncology patients exhibiting cardiotoxicity.
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August 31, 2019
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Abstract at ESC Congress 2019
CMR fast-SENC intramyocardial LV & RV segmental strain detects cardiotoxicity during oncology treatment and impact of cardioprotection therapy before echocardiography
This abstract utilizes MyoStrain in the early detection of cardiotoxicity for patients undergoing oncology treatment, as compared to echocardiography. The abstract also examines the effectiveness of cardio-protection, utilizing MyoStrain to monitor and manage the effects of cardioprotective therapy on patient heart function.
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August 31, 2019
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Abstract at ESC Congress 2019
Cardiac magnetic resonance imaging-based myocardial strain study for evaluation of cardiotoxicity in breast cancer patients treated with trastuzumab: A pilot study to evaluate the feasibility of the method
Authors utilize MyoStrain's myocardial strain assessment to quantify subclinical cardiotoxicity in breast cancer patients exposed to trastuzumab-based chemotherapy.
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May 13, 2016
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Cardiology Journal
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