MyoStrain is Transforming the Cardiac & Cancer Care Continuum

MyoStrain is transforming the way physicians manage and monitor patient heart health, providing a proactive, patient-centric solution to help physicians improve outcomes and prevent heart failure.

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Using Segmental Strain to Overcome Diagnostic Limitations

Today's diagnostics often cannot detect heart dysfunction until symptoms occur. MyoStrain utilizes segmental strain to measure 48 segments of the heart and provides physicians with a unique diagnostic tool to help identify regional dysfunction before the heart as a whole is affected.

segmental myocardial strain visualized on 3d myostrain heart model
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More About Segmental Strain

What Does Segmental Strain Do Differently?

MyoStrain uses segmental strain to help physicians detect regional heart dysfunction early and before global heart function is impacted.¹ Measured across 48 segments of the heart, MyoStrain helps physicians determine weaker areas of the heart where abnormal contraction is occurring.


Measuring Heart Contraction: Segmental vs. Global

As shown below, using segmental strain allows physicians to differentiate and measure weak, or abnormal, heart segments. Conversely, because global strain measures the heart as a whole, healthy segments often overcompensate for abnormal segments, making the heart appear healthy.

segmental myocardial strain vs global myocardial strain diagram
REFERENCES
1. Montenbruck M, et al. CMR fast-SENC segmental intramyocardial LV strain detects heart disease progression based on ACC/AHA Heart Failure stage before global longitudinal strain or ejection fraction. ESC Congress 2019. P600.
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MyoStrain Testing May Change Cardiac Patient Management

The proprietary and non-invasive MyoStrain® test is a 10-minute, quantitative heart function assessment using high-speed MRI to help physicians detect early dysfunction across 48 segments of the heart.

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Rapid & Safe

Patients undergo a 12-heartbeat MRI scan without the need for radiation, contrast, or breath-hold

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Quantitative

Directly measures the percentage of normally contracting myocardium across 48 segments

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Standardized

Provides high reproducibility across sites, operators and MR vendors

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Personalized

Creates a personalized patient report, helping physicians make individualized treatment decisions

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Results Simplified Into One MyoHealth Score

The rapid and accurate MyoStrain test produces a comprehensive report detailing a patient's heart function and calculates the patient's MyoHealth™ score. The MyoHealth™ score is a single number indicating the percentage of normally functioning heart muscle tissue in the left ventricle.

simplified myohealth score acquired from myostrain patient report
myohealth patient progress on mobile phone app
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Monitoring & Managing Patient Heart Health Over Time

The MyoHealth™ score helps physicians to better understand their patient's heart health. By enabling physicians to monitor the effects of disease and treatments on the heart over time, the MyoHealth score empowers physicians to individualize care and manage cardio-protective therapy through the course of cancer treatment.

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MyoStrain has Multiple Clinical Applications Across Large Unmet Markets

nurse shares myostrain results with cancer patient
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Protecting the Heart During Cancer Therapy

For cancer patients who may be at a higher risk of developing heart failure, the MyoHealth score provides solutions to help cardio-oncologists manage cardio-protection over time without interfering with cancer treatment.

Cardio-Oncology >
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Improving Chest Pain Triage & Workflow in the ER

Over 10 million Americans visit the ER with unexplained chest pain symptoms every year.¹ In 10-15 minutes, the MyoHealth score may help physicians to quickly risk stratify patients and refer patients towards optimal treatment pathways.

Chest Pain Triage >
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Detecting Cardiac Effects of Chronic Diseases Early to Prevent Heart Failure

Nearly half of Americans will have some form of cardiovascular disease by 2035.² MyoStrain helps physicians to quantify the effects of heart diseases on patient heart function, enabling preventative care pathways for patients at risk of heart failure.

Preventative Care >
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Managing Acute Heart Failure Treatment for Improved Quality of Life

Over half of acute heart failure patients are re-hospitalized within six months.³ MyoHealth scores help physicians monitor and manage the effects of treatment to reduce hospitalizations and improve quality of life.

Heart Failure Management >

REFERENCES

1. Hsia R. et al. A National Study of the Prevalence of Life-Threatening Diagnoses in Patients With Chest Pain. JAMA Intern Med. 2016;176(7):1029-1032. doi:10.1001/jamainternmed.2016.2498
2. American Heart Association. CVD Burden Report 2017.
3. Lesyuk W, et al. BMC Cardio D 2018.
4. Savarese G, et al. Card Fail Rev 2017. doi:10.15420/cfr.2016:25:2