RESEARCH

MyoStrain’s technology has been validated in over 250 published articles
and used in over 70 major medical research centers worldwide

Strain Research

Strain measures have shown to be better markers of mortality and morbidity than ejection fraction [07]

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Founded in 2009

Myocardial Solutions’ core MRI technologies were co-developed at Johns Hopkins University

Our history

Published Literature

  • Cardiomyopathy
  • Chemotherapy / Cardiotoxicity
  • Coronary Artery Disease (CAD)
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Research Highlights

Myocardial Strain Parameters for Measuring Heart Function

Strain provides accurate measures of left ventricular function and can be analyzed using specific parameters. Neizel M, et al. Strain-Encoded MRI for Evaluation of Left Ventricular Function and Transmurality in Acute Myocardial Infarction. Circulation Cardiovascular Imaging. 2009;2:116-122.
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Quantifying Heart Function

Oyama-Manabe N, et al. Identification and further differentiation of subendocardial and transmural myocardial infarction by fast strain-encoded (SENC) magnetic resonance imaging at 3.0 Tesla. European Radiology. 2011;21(11):2362-2368.
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The Prognostic Value of Strain in Heart Failure

Myocardial strain measurements provide prognostic value regarding the development of heart failure. Choi EY, et al. Prognostic value of myocardial circumferential strain for incident heart failure and cardiovascular events in asymptomatic individuals: the Multi-Ethnic Study of Atherosclerosis. European Heart Journal. 2013;34:2354-2361.
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Company History

Myocardial Solutions’ strain measurement technology was developed at Johns Hopkins University by leading cardiac MRI expert and MSI founder, Nael Osman. Through our research products, HARP and VIRTUE, the technology became the gold standard for strain. In order to make strain measurements available for clinical use, Myocardial Solutions optimized its technology with MyoStrain, making it ideal for widespread adoption combining the technology’s accuracy with rapid speed and ease-of-use.

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10 Minute Exam, 6 Heartbeat Scan,
37 Region Analysis, 1 Quantitative Diagnostic Report

Heart Failure Detection - MyoStrain

Empowering physicians with a
proactive approach

See how MyoStrain improves
treatment decisions

MyoStrain measures the effects of coronary artery disease on heart function

Published Strain Literature by Subject

MyoStrain’s technology is validated in predecessor products HARP, VIRTUE and SENC.

Myocardial Infarction

Myocardial infarction (from Latin: Infarctus myocardii, MI) or acute myocardial infarction (AMI) is the medical term for an event commonly known as a heart attack. An MI occurs when blood stops flowing properly to a part of the heart, and the heart muscle is injured because it is not receiving enough oxygen. Usually this is because...
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Left Ventricle

The left ventricle (LV) is one of four chambers (two atria and two ventricles) in the human heart. It is the largest muscle of all the chambers as it is responsible to pump the blood to most of the body.  It receives oxygenated blood from the left atrium via the mitral valve, and pumps it...
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Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy (HCM) is the most common cardiomyopathy.  It results in an unhealthy thickening of the heart wall, which leads, in many cases, to obstructing the blood flow through the aortic valve, or compromises the function of the aortic valve. Function of the LV wall changes in different regions as the disease progresses, and one...
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Contact Us

We work with Medical Research Centers, MRI Manufacturers,
Outpatient Imaging Centers and Physicians

Myocardial Solutions' technology has been used globally in over 70 major medical research centers and is established as the gold standard for strain measurement. The research has yielded over 250 articles in peer-reviewed journals (50 articles from Circulation and JACC alone) that validate CMR strain testing. MyoStrain’s predecessor software (HARP & VIRTUE) have 510(k) clearance and CE Mark certification.
MyoStrain has CE mark certification, and Myocardial Solutions is actively pursuing FDA 510(k) clearance for MyoStrain.